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Current CME
Cardiology Updates 2024
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Diabetes Management
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Acute Myocardial Infarction
Pathophysiology
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Acute myocardial infarction (AMI) is one of the leading causes of death in the developed world. The prevalence of the disease approaches 3 million people worldwide, with more than 1 million deaths in the United States annually. AMI can be divided into 2 categories: non–ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI)...
Acute myocardial infarction occurs due to decreased coronary blood flow, leading to insufficient oxygen supply to the heart and cardiac ischemia. Decreased coronary blood flow is multifactorial. Atherosclerotic plaques classically rupture and lead to thrombosis, contributing to acutely decreased blood flow in the coronary...
Approximately 70% of fatal AMI cases are attributed to occlusion caused by atherosclerotic plaques. As atherosclerosis is the predominant cause of AMI, risk-factors for atherosclerotic disease are often mitigated in disease prevention. Modifiable risk factors account for 90% of AMI cases in men and 94% in women...
The rupture of an atherosclerotic plaque initiates an inflammatory response of monocytes and macrophages, leading to thrombus formation and platelet aggregation. This process decreases oxygen delivery through the coronary artery, resulting in inadequate oxygenation of the myocardium...
Acute Myocardial Infarction
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Acute Myocardial Infarction
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